The ameliorative effect of Primula vulgaris on cisplatin-induced nephrotoxicity in rats and quantification of its phenolic components using LC-ESI-MS/MS

The ameliorative effect of Primula vulgaris on cisplatin-induced nephrotoxicity in rats and quantification of its phenolic components using LC-ESI-MS/MS

Cisplatin (CDDP) is an important chemotherapeutic agent, accumulation of which in kidney tissue causes nephrotoxicity and renal failure. The aim of this study was to evaluate, for the first time in the literature, the protective effect of dimethyl sulfoxide (DMSO) extract of Primula vulgaris leaf (P...

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Bibliographic Details
Main Authors: Ibrahim Turan, Deniz Canbolat, Selim Demir, Gokcen Kerimoglu, Fatih Colak, Nihal Turkmen Alemdar, Ahmet Mentese, Yüksel Aliyazicioglu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Saudi Pharmaceutical Journal
Subjects:
Apoptosis
Cisplatin
Nephrotoxicity
LC-MS-MS
Primula vulgaris
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016423002256

Internet

http://www.sciencedirect.com/science/article/pii/S1319016423002256

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