Structural mechanism of ATP-independent transcription initiation by RNA polymerase I

Structural mechanism of ATP-independent transcription initiation by RNA polymerase I

Transcription initiation by RNA Polymerase I (Pol I) depends on the Core Factor (CF) complex to recognize the upstream promoter and assemble into a Pre-Initiation Complex (PIC). Here, we solve a structure of Saccharomyces cerevisiae Pol I-CF-DNA to 3.8 Å resolution using single-particle cryo-electro...

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Bibliographic Details
Main Authors: Yan Han, Chunli Yan, Thi Hoang Duong Nguyen, Ashleigh J Jackobel, Ivaylo Ivanov, Bruce A Knutson, Yuan He
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
transcription
RNA polymerase I
core factor
initiation complex
gene expression
ribosomal RNA
Online Access:https://elifesciences.org/articles/27414

Internet

https://elifesciences.org/articles/27414

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