Impact of the gonococcal FC428 penA allele 60.001 on ceftriaxone resistance and biological fitness

ABSTRACTGlobal dissemination of the Neisseria gonorrhoeae ceftriaxone-resistant FC428 clone jeopardizes the currently recommended ceftriaxone-based first-line therapies. Ceftriaxone resistance in the FC428 clone has been associated with the presence of its mosaic penA allele 60.001. Here we investig...

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Bibliographic Details
Main Authors: Ke Zhou, Shao-Chun Chen, Fan Yang, Stijn van der Veen, Yue-Ping Yin
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1773325