<i>Leishmania tarentolae</i> as an Antigen Delivery Platform: Dendritic Cell Maturation after Infection with a Clone Engineered to Express the SARS-CoV-2 Spike Protein

<i>Leishmania tarentolae</i> as an Antigen Delivery Platform: Dendritic Cell Maturation after Infection with a Clone Engineered to Express the SARS-CoV-2 Spike Protein

Background: Protozoa of the genus <i>Leishmania</i> are characterized by their capacity to target macrophages and Dendritic Cells (DCs). These microorganisms could thus be exploited for the delivery of antigens to immune cells. <i>Leishmania tarentolae</i> is regarded as a no...

Full description

Bibliographic Details
Main Authors: Ilaria Varotto-Boccazzi, Micaela Garziano, Giulia Maria Cattaneo, Beatrice Bisaglia, Paolo Gabrieli, Mara Biasin, Alessandro Manenti, Diego Rubolini, Mario Clerici, Emanuele Montomoli, Gian Vincenzo Zuccotti, Daria Trabattoni, Sara Epis, Claudio Bandi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Vaccines
Subjects:
antigen vehicle
dendritic cells
SARS-CoV-2
antigen delivery
cytokines
Online Access:https://www.mdpi.com/2076-393X/10/5/803

Internet

https://www.mdpi.com/2076-393X/10/5/803

Similar Items