Novel 6-Aminoquinazolinone Derivatives as Potential Cross GT1-4 HCV NS5B Inhibitors

Novel 6-Aminoquinazolinone Derivatives as Potential Cross GT1-4 HCV NS5B Inhibitors

Chronic hepatitis C virus (HCV) infections are a worldwide medical problem responsible for diverse types of liver diseases. The NS5B polymerase enzyme has become a very interesting target for the development of anti-HCV drugs owing to its fundamental role in viral replication. Here we report the syn...

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Bibliographic Details
Main Authors: Tamer Nasr, Ahmed M. Aboshanab, George Mpekoulis, Antonios Drakopoulos, Niki Vassilaki, Grigoris Zoidis, Khaled A. M. Abouzid, Wafaa Zaghary
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Viruses
Subjects:
6-Aminoquinazolinone
molecular docking
Hepatitis C
Anti HCV
NS5B inhibitors
daclatasvir
Online Access:https://www.mdpi.com/1999-4915/14/12/2767

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https://www.mdpi.com/1999-4915/14/12/2767

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