An in vivo control map for the eukaryotic mRNA translation machinery

An in vivo control map for the eukaryotic mRNA translation machinery

Rate control analysis defines the in vivo control map governing yeast protein synthesis and generates an extensively parameterized digital model of the translation pathway. Among other non‐intuitive outcomes, translation demonstrates a high degree of functional modularity and comprises a non‐stoichi...

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Bibliographic Details
Main Authors: Helena Firczuk, Shichina Kannambath, Jürgen Pahle, Amy Claydon, Robert Beynon, John Duncan, Hans Westerhoff, Pedro Mendes, John EG McCarthy
Format: Article
Language:English
Published: Springer Nature 2013-01-01
Series:Molecular Systems Biology
Subjects:
eukaryotic translation machinery
gene duplication
in vivo rate control
post‐transcriptional gene expression
system modularity
Online Access:https://doi.org/10.1038/msb.2012.73

Internet

https://doi.org/10.1038/msb.2012.73

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