Chirality of Novel Bitopic Agonists Determines Unique Pharmacology at the Dopamine D3 Receptor
The dopamine D2/D3 receptor (D<sub>2</sub>R/D<sub>3</sub>R) agonists are used as therapeutics for Parkinson’s disease (PD) and other motor disorders. Selective targeting of D<sub>3</sub>R over D<sub>2</sub>R is attractive because of D<sub>3</s...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/4/570 |