Discovery of New Ginsenol-Like Compounds with High Antiviral Activity

Discovery of New Ginsenol-Like Compounds with High Antiviral Activity

A number of framework amides with a ginsenol backbone have been synthesized using the Ritter reaction. We named the acetamide as Ginsamide. A method was developed for the synthesis of the corresponding amine and thioacetamide. The new compounds revealed a high activity against H1N1 influenza, which...

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Bibliographic Details
Main Authors: Aleksandrina S. Volobueva, Olga I. Yarovaya, Marina V. Kireeva, Sophia S. Borisevich, Kseniya S. Kovaleva, Iliya Ya. Mainagashev, Yuri V. Gatilov, Margarita G. Ilyina, Vladimir V. Zarubaev, Nariman F. Salakhutdinov
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
Ginsenol
Ginsamide
antiviral agent
surface protein
influenza
resistance
Online Access:https://www.mdpi.com/1420-3049/26/22/6794

Internet

https://www.mdpi.com/1420-3049/26/22/6794

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