Heritability of the glycan clock of biological age

Heritability of the glycan clock of biological age

Immunoglobulin G is posttranslationally modified by the addition of complex N-glycans affecting its function and mediating inflammation at multiple levels. IgG glycome composition changes with age and health in a predictive pattern, presumably due to inflammaging. As a result, a novel biological agi...

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Bibliographic Details
Main Authors: Anika Mijakovac, Azra Frkatović, Maja Hanić, Jelena Ivok, Marina Martinić Kavur, Maja Pučić-Baković, Tim Spector, Vlatka Zoldoš, Massimo Mangino, Gordan Lauc
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
heritability
glycan clock
aging biomarker
biological age
IgG glycosylation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.982609/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.982609/full

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