A novel estrogen-targeted PEGylated liposome co-delivery oxaliplatin and paclitaxel for the treatment of ovarian cancer

A novel estrogen-targeted PEGylated liposome co-delivery oxaliplatin and paclitaxel for the treatment of ovarian cancer

Ovarian cancer is the second cause of death among gynecological malignancies. In this study, we designed a novel estrogen-targeted PEGylated liposome loaded with oxaliplatin and paclitaxel (ES-SSL-OXA/PTX) which could target estrogen receptor (ER) highly expressed on the surface of SKOV-3 cells to e...

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Bibliographic Details
Main Authors: Yizhuo Xie, Zhihui Ren, Hongyu Chen, Huan Tang, Ming Zhu, Zhe Lv, Han Bao, Yan Zhang, Rui Liu, Yujia Shen, Yucui Zheng, Dongfanghui Miao, Xin Guo, Hongli Chen, Shanshan Wang, Jin Pei
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ovarian cancer
Estrogen receptor
Combined chemotherapy
Active targeting
Liposome
Anti-tumor efficacy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223000926

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http://www.sciencedirect.com/science/article/pii/S0753332223000926

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