How Can Immune Checkpoint Inhibitors Cause Hyperprogression in Solid Tumors?

Following the administration of immune checkpoint inhibitors, an unexpected pattern of response designated as hyperprogression may be observed in certain patients. This paradoxical response corresponds to an acceleration in tumor growth and a dramatic decrease of patient survival. The reported incid...

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Bibliographic Details
Main Authors: Morgane Denis, Michael Duruisseaux, Marie Brevet, Charles Dumontet
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00492/full