The Transcription Factor AHR Prevents the Differentiation of a Stage 3 Innate Lymphoid Cell Subset to Natural Killer Cells

The Transcription Factor AHR Prevents the Differentiation of a Stage 3 Innate Lymphoid Cell Subset to Natural Killer Cells

Accumulating evidence indicates that human natural killer (NK) cells develop in secondary lymphoid tissue (SLT) through a so-called “stage 3” developmental intermediate minimally characterized by a CD34−CD117+CD94− immunophenotype that lacks mature NK cell function. This stage 3 population is hetero...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Tiffany Hughes, Edward L. Briercheck, Aharon G. Freud, Rossana Trotta, Susan McClory, Steven D. Scoville, Karen Keller, Youcai Deng, Jordan Cole, Nicholas Harrison, Charlene Mao, Jianying Zhang, Don M. Benson, Jianhua Yu, Michael A. Caligiuri
Format: Artikel
Sprache:English
Veröffentlicht: Elsevier 2014-07-01
Schriftenreihe:Cell Reports
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2211124714004367

Online

http://www.sciencedirect.com/science/article/pii/S2211124714004367

Ähnliche Einträge