A Non-Invasive Strategy for Neonatal Alloimmune Thrombocytopenia Diagnosis: Newborn Platelet Genotyping with Buccal Swabs

A Non-Invasive Strategy for Neonatal Alloimmune Thrombocytopenia Diagnosis: Newborn Platelet Genotyping with Buccal Swabs

Neonatal alloimmune thrombocytopenia results from the maternal immune response against fetal-specific antigens inherited from the father. The diagnosis is ascertained only when the maternal alloantibody and the offending antigen present in the newborn are identified. Up until now most laboratories p...

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Bibliographic Details
Main Authors: Gérald Bertrand, Cécile Kaplan
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:International Journal of Neonatal Screening
Subjects:
neonatal alloimmune thrombocytopenia (NAIT)
Human Platelet Antigen (HPA)
genotyping
buccal swab
DNA extraction
Online Access:http://www.mdpi.com/2409-515X/2/3/3

Internet

http://www.mdpi.com/2409-515X/2/3/3

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