Applying intensified design of experiments to mammalian cell culture processes

Applying intensified design of experiments to mammalian cell culture processes

Abstract The analysis of data collected using design of experiments (DoE) is the current gold standard to determine the influence of input parameters and their interactions on process performance and product quality. In early development, knowledge on the bioprocess of a new product is limited. Many...

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Bibliographic Details
Main Authors: Verena Nold, Lisa Junghans, Lorenzo Bisgen, Raphael Drerup, Beate Presser, Ingo Gorr, Thomas Schwab, Bettina Knapp, Stefan Wieschalka
Format: Article
Language:English
Published: Wiley-VCH 2022-12-01
Series:Engineering in Life Sciences
Subjects:
best‐cost strategy
early stage development
industrial mammalian cell culture
intensified design of experiments
modeling upstream bioprocessing
Online Access:https://doi.org/10.1002/elsc.202100123

Internet

https://doi.org/10.1002/elsc.202100123

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