The mechanism of gentisic acid-induced relaxation of the guinea pig isolated trachea: the role of potassium channels and vasoactive intestinal peptide receptors

We examined some of the mechanisms by which the aspirin metabolite and the naturally occurring metabolite gentisic acid induced relaxation of the guinea pig trachea in vitro. In preparations with or without epithelium and contracted by histamine, gentisic acid caused concentration-dependent and repr...

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Bibliographic Details
Main Authors: J.F. Cunha, F.D. Campestrini, J.B. Calixto, A. Scremin, N. Paulino
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000300013