EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion

EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion

Objectives: Readily accessible human pancreatic beta cells that are functionally close to primary adult beta cells are a crucial model to better understand human beta cell physiology and develop new treatments for diabetes. We here report the characterization of EndoC-βH5 cells, the latest in the En...

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Bibliographic Details
Main Authors: Bruno Blanchi, Marion Taurand, Claire Colace, Sofia Thomaidou, Charlotte Audeoud, Federica Fantuzzi, Toshiaki Sawatani, Sevda Gheibi, Joan Sabadell-Basallote, Fransje W.J. Boot, Thibault Chantier, Aline Piet, Charlotte Cavanihac, Marion Pilette, Adélie Balguerie, Hamza Olleik, Françoise Carlotti, Miriam Ejarque, Malin Fex, Hindrik Mulder, Miriam Cnop, Decio L. Eizirik, Ouardane Jouannot, Anne-Lise Gaffuri, Paul Czernichow, Arnaud Zaldumbide, Raphaël Scharfmann, Philippe Ravassard
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Molecular Metabolism
Subjects:
Human pancreatic beta cell line
Human beta cell function
Glucose and incretin stimulated insulin secretion
Type-I diabetes disease model
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823001060

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http://www.sciencedirect.com/science/article/pii/S2212877823001060

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