Metformin in Differentiated Thyroid Cancer: Molecular Pathways and Its Clinical Implications

Metformin is a synthetic biguanide that improves insulin sensitivity and reduces hepatic gluconeogenesis. Aside being the first-line therapy for Type 2 Diabetes (T2D), many pleiotropic effects have been discovered in recent years, such as its capacity to reduce cancer risk and tumorigenesis. Althoug...

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Bibliographic Details
Main Authors: Manuel García-Sáenz, Miry Lobaton-Ginsberg, Aldo Ferreira-Hermosillo
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/4/574