Comparison of mechanisms of kinetochore capture with varying number of spindle microtubules

The biophysical mechanisms of kinetochore capture by spindle microtubules within cells are stochastic processes with a moving target searched by multiple walkers inside a confined volume. We study and compare two such mechanisms: dynamic instability-driven search and capture, common in many eukaryot...

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Bibliographic Details
Main Authors: Indrani Nayak, Dibyendu Das, Amitabha Nandi
Format: Article
Language:English
Published: American Physical Society 2020-02-01
Series:Physical Review Research
Online Access:http://doi.org/10.1103/PhysRevResearch.2.013114