Proteomic Analysis of ISGylation in Immortalized Porcine Alveolar Macrophage Cell Lines Induced by Type I Interferon

Proteomic Analysis of ISGylation in Immortalized Porcine Alveolar Macrophage Cell Lines Induced by Type I Interferon

Interferon-stimulated gene product 15 (ISG15), a ubiquitin-like molecule, can be conjugated to protein substrates through a reversible process known as ISGylation. ISG15 and ISGylation are both strongly upregulated by type I interferons and play putative key roles in host innate immunity against vir...

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Bibliographic Details
Main Authors: Chengbo Zhu, Jingrui Li, Chaonan Tian, Mengmeng Qin, Zhenni Wang, Bingjun Shi, Guanggang Qu, Chunyan Wu, Yuchen Nan
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Vaccines
Subjects:
interferons
interferons-stimulated genes (ISGs), ISG15
ISGylation
ubiquitination
Online Access:https://www.mdpi.com/2076-393X/9/2/164

Internet

https://www.mdpi.com/2076-393X/9/2/164

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