Neuroprotective Effect of a CNTF-Expressing Lentiviral Vector in the Quinolinic Acid Rat Model of Huntington's Disease

Neuroprotective Effect of a CNTF-Expressing Lentiviral Vector in the Quinolinic Acid Rat Model of Huntington's Disease

Neurodegenerative diseases represent promising targets for gene therapy approaches provided effective transfer vectors. In the present study, we evaluated the effectiveness of LacZ-expressing lentiviral vectors with two different internal promoters, the mouse phosphoglycerate kinase 1 (PGK) and cyto...

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Bibliografische gegevens
Hoofdauteurs: L.Pereira de Almeida, D. Zala, P. Aebischer, N. Déglon
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 2001-06-01
Reeks:Neurobiology of Disease
Onderwerpen:
Huntington's disease
lentiviral vector
gene therapy
ciliary neurotrophic factor
quinolinic acid lesion model
Online toegang:http://www.sciencedirect.com/science/article/pii/S0969996101903882

Internet

http://www.sciencedirect.com/science/article/pii/S0969996101903882

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