Dysregulated Genes, MicroRNAs, Biological Pathways, and Gastrocnemius Muscle Fiber Types Associated With Progression of Peripheral Artery Disease: A Preliminary Analysis

Dysregulated Genes, MicroRNAs, Biological Pathways, and Gastrocnemius Muscle Fiber Types Associated With Progression of Peripheral Artery Disease: A Preliminary Analysis

Background Peripheral artery disease (PAD) is associated with gastrocnemius muscle abnormalities. However, the biological pathways associated with gastrocnemius muscle dysfunction and their associations with progression of PAD are largely unknown. This study characterized differential gene and micro...

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Bibliographic Details
Main Authors: Sunil K. Saini, Daniel Pérez‐Cremades, Henry S. Cheng, Kate Kosmac, Charlotte A Peterson, Lingyu Li, Lu Tian, Gengfu Dong, Kevin K. Wu, Brian Bouverat, Stephanie E. Wohlgemuth, Terence Ryan, Robert L. Sufit, Luigi Ferrucci, Mary M. McDermott, Christiaan Leeuwenburgh, Mark W. Feinberg
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
differentially expressed genes (DEG)
gastrocnemius muscle
peripheral artery disease (PAD)
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.023085

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https://www.ahajournals.org/doi/10.1161/JAHA.121.023085

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