Construction and Immunogenicity of a Recombinant Pseudorabies Virus Variant With TK/gI/gE/11k/28k Deletion

Construction and Immunogenicity of a Recombinant Pseudorabies Virus Variant With TK/gI/gE/11k/28k Deletion

In China, the re-emerging pseudorabies virus (PRV) variant has caused large-scale outbreaks of pseudorabies in swine herds with classical PRV vaccine immunization since late 2011. Here, a recombinant PRV with TK/gI/gE/11k/28k deletion was constructed based on variant HN1201 strain isolated in 2012,...

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Bibliographic Details
Main Authors: Shijun Yan, Baicheng Huang, Xiaofei Bai, Ying Zhou, Linghua Guo, Tongyan Wang, Yihong Shan, Yuzhou Wang, Feifei Tan, Kegong Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Veterinary Science
Subjects:
pseudorabies virus (PRV)
gene deletion
bacterial artificial chromosome
vaccine
immune protection
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2021.797611/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2021.797611/full

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