Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Mice with ectopic expression of uncoupling protein-1 (UCP1) in skeletal muscle exhibit a healthy aging phenotype with increased longevity and resistance to impaired metabolic health. This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). We investigated...
| Main Authors: | , , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Elsevier
2023-02-01
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| 叢編: | Redox Biology |
| 主題: | |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2213231722003469 |