Design and development of thermosensitive rectal in situ gel from Luffa acutangula fruits for the treatment of ulcerative colitis

Design and development of thermosensitive rectal in situ gel from Luffa acutangula fruits for the treatment of ulcerative colitis

Background: Luffa acutangula has good anti-inflammatory and antioxidant activity.  Ulcerative colitis has inflamed intestinal mucosal lining with frequent diarrhoea, mucosal, and bloody stools. The rectal administration provides high bioavailability, rapid absorption, and instant therapeutic effect....

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Bibliographic Details
Main Authors: Swati P. Barangule, Avish D. Maru
Format: Article
Language:English
Published: Creative Pharma Assent 2024-10-01
Series:Journal of Applied Pharmaceutical Research
Subjects:
in situ gel
thermosensitive polymer
luffa acutangula
poloxamer
mucoadhesive
Online Access:https://japtronline.com/index.php/joapr/article/view/761

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https://japtronline.com/index.php/joapr/article/view/761

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