HSP47 in human diseases: Navigating pathophysiology, diagnosis and therapy

Abstract Heat shock protein 47 (HSP47) is a chaperone protein responsible for regulating collagen maturation and transport, directly impacting collagen synthesis levels. Aberrant HSP47 expression or malfunction has been associated with collagen‐related disorders, most notably fibrosis. Recent report...

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Bibliographic Details
Main Authors: Essak. S. Khan, Tobias Däinghaus
Format: Article
Language:English
Published: Wiley 2024-08-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.1755