Neutrophils contribute to elevated BAFF levels to modulate adaptive immunity in patients with primary immune thrombocytopenia by CD62P and PSGL1 interaction

Neutrophils contribute to elevated BAFF levels to modulate adaptive immunity in patients with primary immune thrombocytopenia by CD62P and PSGL1 interaction

Abstract Objectives Immune thrombocytopenia (ITP) is an autoimmune disease characterised by impaired platelet production and increased platelet destruction. However, the involvement of neutrophils in ITP is yet to be explored. Methods B‐cell activating factor (BAFF) expression and activation markers...

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Bibliographic Details
Main Authors: Pengcheng Xu, Xia Shao, Yang Ou, Yanxia Zhan, Lili Ji, Xibing Zhuang, Ying Li, Yanna Ma, Duojiao Wu, Tiankui Qiao, Xiangdong Wang, Hao Chen, Yunfeng Cheng
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Clinical & Translational Immunology
Subjects:
acquired immunity
BAFF
CD62P
neutrophils
primary immune thrombocytopenia
Online Access:https://doi.org/10.1002/cti2.1399

Internet

https://doi.org/10.1002/cti2.1399

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