FASN multi-omic characterization reveals metabolic heterogeneity in pancreatic and prostate adenocarcinoma

FASN multi-omic characterization reveals metabolic heterogeneity in pancreatic and prostate adenocarcinoma

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) and prostate cancer (PCa) are among the most prevalent malignant tumors worldwide. There is now a comprehensive understanding of metabolic reprogramming as a hallmark of cancer. Fatty acid synthase (FASN) is a key regulator of the lipid met...

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Bibliographic Details
Main Authors: Ugo Chianese, Chiara Papulino, Ahmad Ali, Fortunato Ciardiello, Salvatore Cappabianca, Lucia Altucci, Vincenzo Carafa, Rosaria Benedetti
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Translational Medicine
Subjects:
FASN
Pancreatic adenocarcinoma
Prostate adenocarcinoma
Metabolism
Proliferation
Online Access:https://doi.org/10.1186/s12967-023-03874-5

Internet

https://doi.org/10.1186/s12967-023-03874-5

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