Pilot study of circulating cell-free mitochondrial DNA in relation to brain structure in youth bipolar disorder

Pilot study of circulating cell-free mitochondrial DNA in relation to brain structure in youth bipolar disorder

Abstract Background Mitochondrial dysfunction is implicated in the neuropathology of bipolar disorder (BD). Higher circulating cell-free mitochondrial DNA (ccf-mtDNA), generally reflecting poorer mitochondrial health, has been associated with greater symptoms severity in BD. The current study examin...

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Bibliographic Details
Main Authors: Suyi Shao, Yi Zou, Kody G. Kennedy, Mikaela K. Dimick, Ana C. Andreazza, L. Trevor Young, Vanessa F. Goncalves, Bradley J. MacIntosh, Benjamin I. Goldstein
Format: Article
Language:English
Published: SpringerOpen 2024-06-01
Series:International Journal of Bipolar Disorders
Subjects:
mtDNA
Bipolar disorder
Mitochondria
Magnetic resonance imaging
Youth
Online Access:https://doi.org/10.1186/s40345-024-00334-x

Internet

https://doi.org/10.1186/s40345-024-00334-x

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