Neutralizing Monoclonal Anti-SARS-CoV-2 Antibodies Isolated from Immunized Rabbits Define Novel Vulnerable Spike-Protein Epitope

Neutralizing Monoclonal Anti-SARS-CoV-2 Antibodies Isolated from Immunized Rabbits Define Novel Vulnerable Spike-Protein Epitope

Monoclonal antibodies represent an important avenue for COVID-19 therapy and are routinely used for rapid and accessible diagnosis of SARS-CoV-2 infection. The recent emergence of SARS-CoV-2 genetic variants emphasized the need to enlarge the repertoire of antibodies that target diverse epitopes, th...

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Bibliographic Details
Main Authors: Efi Makdasi, Yinon Levy, Ron Alcalay, Tal Noy-Porat, Eran Zahavy, Adva Mechaly, Eyal Epstein, Eldar Peretz, Hila Cohen, Liat Bar-On, Theodor Chitlaru, Ofer Cohen, Itai Glinert, Hagit Achdout, Tomer Israely, Ronit Rosenfeld, Ohad Mazor
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
COVID-19
SARS-CoV-2
neutralizing antibody
monoclonal antibody
single-cell sort
spike
Online Access:https://www.mdpi.com/1999-4915/13/4/566

Internet

https://www.mdpi.com/1999-4915/13/4/566

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