Edaravone exerts brain protective function by reducing the expression of AQP4, APP and Aβ proteins

Edaravone exerts brain protective function by reducing the expression of AQP4, APP and Aβ proteins

This study aims to investigate the changes of aquaporin-4 (AQP4), β-amyloid precursor proteins (APP) and β-amyloid (Aβ) in brain tissues after cerebral ischemiareperfusion injury (CIRI), and evaluate the effect of edaravone. The Middle Cerebral Artery Occlusion was used to establish CIRI in rats. Ra...

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Bibliographic Details
Main Authors: Ren Haiyan, Ma Lijuan, Gong Xueli, Xu Chenbo, Zhang Yuge, Ma Meilei, Watanabe Kenichi, Wen Juan
Format: Article
Language:English
Published: De Gruyter 2019-12-01
Series:Open Life Sciences
Subjects:
cerebral ischemia-reperfusion injury
aquaporin 4
β-amyloid precursor proteins
β-amyloid
edaravone
Online Access:https://doi.org/10.1515/biol-2019-0074

Internet

https://doi.org/10.1515/biol-2019-0074

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