Sub-acute and sub-chronic toxicity assessment of the antimicrobial peptide Dermaseptin B2 on biochemical, haematological and histopathological parameters in BALB/c mice and Albino Wistar rats

Sub-acute and sub-chronic toxicity assessment of the antimicrobial peptide Dermaseptin B2 on biochemical, haematological and histopathological parameters in BALB/c mice and Albino Wistar rats

Background: Dermaseptins (Drs) are peptides found in the skin secretions of a variety of Hylid frogs, particularly those belonging to the Agalychnis and Phyllomedusa families. Dermaseptin B2 (Drs B2), an amphipathic, α-helical polypeptide was reported as the most active of the Dermaseptin B family....

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Bibliographic Details
Main Authors: Ahmed A. Abdille, Shedrack Reuben Kitimu, Mark M. Ndubi, Josephine Kimani, Esther N. Maina, Wallace Bulimo, Yahaya Gavamukulya, Fred Wamunyokoli
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Dermaseptin B2
Antimicrobial peptides
Toxicity
Sub-acute toxicity
Sub-chronic toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022034120

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http://www.sciencedirect.com/science/article/pii/S2405844022034120

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