Hydrogel particles improve detection of SARS-CoV-2 RNA from multiple sample types

Abstract Here we present a rapid and versatile method for capturing and concentrating SARS-CoV-2 from contrived transport medium and saliva samples using affinity-capture magnetic hydrogel particles. We demonstrate that the method concentrates virus from 1 mL samples prior to RNA extraction, substan...

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Bibliographic Details
Main Authors: R. A. Barclay, I. Akhrymuk, A. Patnaik, V. Callahan, C. Lehman, P. Andersen, R. Barbero, S. Barksdale, R. Dunlap, D. Goldfarb, T. Jones-Roe, R. Kelly, B. Kim, S. Miao, A. Munns, D. Munns, S. Patel, E. Porter, R. Ramsey, S. Sahoo, O. Swahn, J. Warsh, K. Kehn-Hall, B. Lepene
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78771-8