Tnpo3 controls splicing of the pre-mRNA encoding the canonical TCR α chain of iNKT cells

Abstract Unconventional T cells, such as innate natural killer T cells (iNKT) cells, are an important part of vertebrate immune defences. iNKT recognise glycolipids through a T cell receptor (TCR) that is composed of a semi-invariant TCR α chain, paired with a restricted set of TCR β chains. Here, w...

Full description

Bibliographic Details
Main Authors: Norimasa Iwanami, Andreas S. Richter, Katarzyna Sikora, Thomas Boehm
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39422-4