Buffering by gene duplicates: an analysis of molecular correlates and evolutionary conservation

<p>Abstract</p> <p>Background</p> <p>One mechanism to account for robustness against gene knockouts or knockdowns is through buffering by gene duplicates, but the extent and general correlates of this process in organisms is still a matter of debate. To reveal general t...

Full description

Bibliographic Details
Main Authors: Vogel Christine, Marcotte Edward M, Hannay Kevin
Format: Article
Language:English
Published: BMC 2008-12-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/609