Metabolic engineering design to enhance (R,R)-2,3-butanediol production from glycerol in Bacillus subtilis based on flux balance analysis

Metabolic engineering design to enhance (R,R)-2,3-butanediol production from glycerol in Bacillus subtilis based on flux balance analysis

Abstract Background Glycerol is a desirable alternative substrate for 2,3-butanediol (2,3-BD) production for sustainable development in biotechnological industries and non-food competitive feedstock. B. subtilis, a “generally recognized as safe” organism that is highly tolerant to fermentation produ...

Full description

Bibliographic Details
Main Authors: Nunthaphan Vikromvarasiri, Tomokazu Shirai, Akihiko Kondo
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Microbial Cell Factories
Subjects:
Glycerol
2,3-Butainediol
Bacillus subtilis
Flux balance analysis
Genome-scale metabolic models
Gene knockout
Online Access:https://doi.org/10.1186/s12934-021-01688-y

Internet

https://doi.org/10.1186/s12934-021-01688-y

Similar Items