Knockdown of the Placental Growth Factor Gene Inhibits Laser Induced Choroidal Neovascularization in a Murine Model

Knockdown of the Placental Growth Factor Gene Inhibits Laser Induced Choroidal Neovascularization in a Murine Model

Purpose: To evaluate the effect of placental growth factor (PlGF) gene knockdown in a murine model of laser-induced choroidal neovascularization. Methods: Choroidal neovascularization was induced in the left eyes of 11 mice by infrared laser. Small interfering RNA (siRNA, 20 picomoles/10 μl) corres...

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Bibliographic Details
Main Authors: Ramin Nourinia, Zahra-Soheila Soheili, Hamid Ahmadieh, Hassan Akrami, Mozhgan Rezaei Kanavi, Shahram Samiei
Format: Article
Language:English
Published: Knowledge E 2013-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Choroidal Neovascularization; Placental Growth Factor; Small Interfering RNA
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2013;volume=8;issue=1;spage=4;epage=8;aulast=Nourinia

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http://www.jovr.org/article.asp?issn=2008-322X;year=2013;volume=8;issue=1;spage=4;epage=8;aulast=Nourinia

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