Dioscin ameliorates doxorubicin‐induced heart failure via inhibiting autophagy and apoptosis by controlling the PDK1‐mediated Akt/mTOR signaling pathway

Abstract Heart failure (HF) is a disease with high mortality and morbidity rate. Autophagy is critically implicated in HF progression. The current research was designed to investigate the function of Dioscin on oxidative stress, autophagy, and apoptosis in HF. In this study, doxorubicin (Dox) was em...

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Bibliographic Details
Main Authors: Ling Yuan, Hai‐Gang Ji, Xiao‐Jing Yan, Meng Liu, Yu‐Han Ding, Xiao‐Hu Chen
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:https://doi.org/10.1002/kjm2.12740