A novel transplantable model of lung cancer-associated tissue loss and disrupted muscle regeneration

Abstract Background Cancer-associated muscle wasting (CAW), a symptom of cancer cachexia, is associated with approximately 20% of lung cancer deaths and remains poorly characterized on a mechanistic level. Current animal models for lung cancer-associated cachexia are limited in that they (1) primari...

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Bibliographic Details
Main Authors: Paige C. Arneson-Wissink, Alexandra M. Ducharme, Jason D. Doles
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Skeletal Muscle
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13395-020-00225-6