Differential analysis of microbiomes in mucus and tissues obtained from colorectal cancer patients

Abstract The outer mucus layer of the colorectal epithelium is easily removable and colonized by commensal microbiota, while the inner mucus layer is firmly attached to the epithelium and devoid of bacteria. Although the specific bacteria penetrating the inner mucus layer can contact epithelial cell...

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Bibliographic Details
Main Authors: Yosuke Tajima, Shujiro Okuda, Tsunekazu Hanai, Junichiro Hiro, Koji Masumori, Yoshikazu Koide, Tadahiro Kamiya, Yeongcheol Cheong, Gaku Inaguma, Yoshifumi Shimada, Toshifumi Wakai, Hayato Takihara, Shingo Akimoto, Hiroshi Matsuoka, Ichiro Uyama, Koichi Suda
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21928-4