Cardioprotective Effects of a Selective c-Jun N-terminal Kinase Inhibitor in a Rat Model of Myocardial Infarction

Cardioprotective Effects of a Selective c-Jun N-terminal Kinase Inhibitor in a Rat Model of Myocardial Infarction

Activation of c-Jun N-terminal kinases (JNKs) is involved in myocardial injury, left ventricular remodeling (LV), and heart failure (HF) after myocardial infarction (MI). The aim of this research was to evaluate the effects of a selective JNK inhibitor, 11<i>H</i>-indeno [1,2-<i>b&...

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Bibliographic Details
Main Authors: Mark B. Plotnikov, Galina A. Chernysheva, Vera I. Smol’yakova, Oleg I. Aliev, Tatyana I. Fomina, Lyubov A. Sandrikina, Irina V. Sukhodolo, Vera V. Ivanova, Anton N. Osipenko, Nina D. Anfinogenova, Andrei I. Khlebnikov, Dmitriy N. Atochin, Igor A. Schepetkin, Mark T. Quinn
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
cardioprotective activity
c-Jun N-terminal kinase inhibitor
11<i>H</i>-indeno[1,2-<i>b</i>]quinoxalin-11-one oxime
heart failure
infarct size
myocardial infarction
Online Access:https://www.mdpi.com/2227-9059/11/3/714

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https://www.mdpi.com/2227-9059/11/3/714

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