Submersion and hypoxia inhibit alveolar epithelial Na+ transport through ERK/NF-κB signaling pathway
Abstract Background Hypoxia is associated with many respiratory diseases, partly due to the accumulation of edema fluid and mucus on the surface of alveolar epithelial cell (AEC), which forms oxygen delivery barriers and is responsible for the disruption of ion transport. Epithelial sodium channel (...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-04-01
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Series: | Respiratory Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12931-023-02428-z |