β-Cyclodextrin Modified Hydrogels of Kappa-Carrageenan for Methotrexate Delivery

This work is aimed at developing a kappa-carrageenan (kCR) gel with increased methotrexate (MTX) content. β-Cyclodextrin (βCD), which is able to inclusion complex formation with MTX, has been used to increase the drug concentration in the hydrogel. The rheological behavior of the designed gels was i...

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Bibliographic Details
Main Authors: Maria Nikitina, Nataliya Kochkina, Marianna Arinina, Valery Kulichikhin, Irina Terekhova
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/9/2244