Tumor Necrosis Factor-α Mediates Lung Injury in the Early Phase of Endotoxemia

Endotoxemia induces lung injury. We assessed the therapeutic efficacy between triple cytokine (tumor necrosis factor-α [TNF-α], interleukin-1β [IL-1β], and IL-6) inhibition (mediated by KCF18 peptide) and single cytokine (TNF-α) inhibition (mediated by SEM18 peptide) on alleviating lung injury in th...

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Bibliographic Details
Main Authors: Kung-Yen Chen, Chao-Yuan Chang, Hao-Jen Hsu, Hung-Jen Shih, I-Tao Huang, Hemal H. Patel, Chun-Jen Huang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/15/3/287