N-Myc Differentially Regulates Expression of MXI1 Isoforms in Neuroblastoma

N-Myc Differentially Regulates Expression of MXI1 Isoforms in Neuroblastoma

Amplification of the MYCN proto-oncogene is associated with a poor prognosis in patients with metastatic neuroblastoma (NB). MYCN encodes the N-Myc protein, a transcriptional regulator that dimerizes with the Max transcription factor, binds to E-box DNA sequences, and regulates genes involved in cel...

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Bibliographic Details
Main Authors: Michael B. Armstrong, Rajen J. Mody, D. Christian Ellis, Adam B. Hill, David A. Erichsen, Daniel S. Wechsler
Format: Article
Language:English
Published: Elsevier 2013-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861380005X

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http://www.sciencedirect.com/science/article/pii/S147655861380005X

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