Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
Despite exciting developments in cancer immunotherapy, its broad application is limited by the paucity of targetable antigens on the tumor cell surface. As an intrinsic cellular pathway, nonsense-mediated decay (NMD) conceals neoantigens through the destruction of the RNA products from genes harbori...
Main Authors: | , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2025-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/95952 |