Engineering an extracellular matrix-functionalized, load-bearing tendon substitute for effective repair of large-to-massive tendon defects

A significant clinical challenge in large-to-massive rotator cuff tendon injuries is the need for sustaining high mechanical demands despite limited tissue regeneration, which often results in clinical repair failure with high retear rates and long-term functional deficiencies. To address this, an i...

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Bibliographic Details
Main Authors: Shuting Huang, Ying Rao, Meng Zhou, Anna M. Blocki, Xiao Chen, Chunyi Wen, Dai Fei Elmer Ker, Rocky S. Tuan, Dan Michelle Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-06-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2400077X