Distinct synaptic pools of DAPK1 differentially regulate activity-dependent synaptic CaMKII accumulation

Distinct synaptic pools of DAPK1 differentially regulate activity-dependent synaptic CaMKII accumulation

Summary: The death-associated protein kinase 1 (DAPK1) regulates the synaptic movement of the Ca2+/calmodulin (CaM)-dependent protein kinase II (CaMKII). Synaptic CaMKII accumulation is mediated via binding to the NMDA-receptor subunit GluN2B and is required for long-term potentiation (LTP). By cont...

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Bibliographic Details
Main Authors: Jonathan E. Tullis, K. Ulrich Bayer
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Molecular neuroscience
Cellular neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223008003

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http://www.sciencedirect.com/science/article/pii/S2589004223008003

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