Incorporation of surface-modified hydroxyapatite into poly(methyl methacrylate) to improve biological activity and bone ingrowth

Incorporation of surface-modified hydroxyapatite into poly(methyl methacrylate) to improve biological activity and bone ingrowth

Poly(methyl methacrylate) (PMMA) is the most frequently used bone void filler in orthopedic surgery. However, the interface between the PMMA-based cement and adjacent bone tissue is typically weak as PMMA bone cement is inherently bioinert and not ideal for bone ingrowth. The present study aims to i...

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Bibliographic Details
Main Authors: Kuan-Lin Ku, Yu-Shan Wu, Chi-Yun Wang, Ding-Wei Hong, Zong-Xing Chen, Ching-An Huang, I-Ming Chu, Po-Liang Lai
Format: Article
Language:English
Published: The Royal Society 2019-05-01
Series:Royal Society Open Science
Subjects:
bone cement
biocompatibility
hydroxyapatite
poly(ɛ-caprolactone)
poly(methyl methacrylate)
surface grafting
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.182060

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https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.182060

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