Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA
DNA methylation occurs on CpG sites and is important to form pericentric heterochromatin domains. The satellite 2 sequence, containing seven CpG sites, is located in the pericentric region of human chromosome 1 and is highly methylated in normal cells. In contrast, the satellite 2 region is reported...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2015-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150128 |