Transforming growth factor-β1/Smad/connective tissue growth factor axis: The main pathway in radiation-induced fibrosis of osteoradionecrosis?
Introduction: Osteoradionecrosis (ORN) of the mandible is a serious complication following radiation therapy for malignancies of the head and neck. Radiation-induced fibrosis (RIF) is a new theory that accounts for the damage to normal tissues after radiotherapy, and the radiation-induced fibroatrop...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2013-01-01
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Series: | Dental Hypotheses |
Subjects: | |
Online Access: | http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2013;volume=4;issue=4;spage=122;epage=126;aulast=Zhuang |